Immunopathogenesis of polymicrobial otitis media

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Immunopathogenesis of polymicrobial otitis media

OM, or inflammation of the middle ear, is a highly prevalent infection in children worldwide. OM is a multifactorial disease with multiple risk factors, including preceding or concurrent viral URT infection. Hence, OM is also a polymicrobial disease. The mechanisms by which viruses predispose to bacterial OM are replete; however, all are predicated on the general principle of compromise of prim...

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Otitis Media

Otitis media is an infection or inflammation of the middle ear. This inflammation often begins when infections that cause sore throats, colds, or other respiratory or breathing problems spread to the middle ear. These can be viral or bacterial infections. Seventy-five percent of children experience at least one episode of otitis media by their third birthday. Almost half of these children will ...

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ژورنال

عنوان ژورنال: Journal of Leukocyte Biology

سال: 2009

ISSN: 0741-5400

DOI: 10.1189/jlb.0709518